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KMID : 1150320060020010055
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Journal of Korean Society of Geriatric Neurosurgery
2006 Volume.2 No. 1 p.55 ~ p.60
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Comparison of Risk Factors and Clinical Findings for Cerebral Infarction between Younger and Elderly Groups in a Single Center
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Choi Hyuk-Jai
Choi Suk-Keun
Kim Gook-Ki
Koh Jun-Seok
Kim Tae-Sung
Rhee Bong-Arm
Lim Young-Jin
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Abstract
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objective: To compare risk factors and clinical findings in patients with cerebral infarction between groups aged over 65 years and under 65 years of age.
Malerials & Methods: From 1 Oct. 2003 to 31 Dec. 2004, the patients who were diagnosed with cerebral infarction by brain CT and/or brain MRI(n 190) were divided into two study groups, patients over 65 years old(n 91) and patients under 65 years old (n=99). Then, a retrospective comparative analysis of their subtypes of infarction, risk factors (sex, hypertension, DM, smoking, hyperlipidemia, obesity), clinical Findings and outcomes was done using medical records.
Results: Of these patients, 91 of them were over 65 years old and 99 were under 65 years old. The male th female was 115:75, and it was 52:39 in patients over 65 years old and 63:36 in patients under 65 years old. According to the NINDS (National institute of Neurological Disorder and Stroke) classifications, 17 patients (18.7%) were cardioembolic infarctions, 33 patients (36.3%) were athcrothrombotic infarctions in the clderly group and 27 patients (27.3%) were cardiocmbolic infarctions, 25 patients (25.3%) were ahterothrombotic infarclions in the younger group. The Elderly group had a significantly higher percentage of atherothrombotic infarction (OR 2.757, P 0.014). With respect to the risk factors, in case of hypertension, the elderly group had 53 patients (58.2%) and the younger group had 46 patients (46.5%). This was the only risk factor which showed a statistically significant difference (OR 0.432, P 0.014). In the elderly group, there were 19 (19.2%) major territory infarctions, and in the younger group, there were 27 (29.7%). Among the major territory infarctions (n 46), 24 (52.2%) of them underwent surgical treatment [elderly group: 6 patients (31.6%), younger group: 18 patients(66.7%)]. While there was a significant difference in the number of surgeries performed, there was no difference in the prognosis between the two groups.
Conclusion: In overall, lacunar intarction was the most common type and the percentage of male pateints was higher in both groups (elderly group: 57.1%, younger group: 63.6%). More than half the patients had history of hypertension and the elder group had a higher incidence. The elderly group had a higher incidence of atherothrombotic than the younger group. The number of patients with major territory infarction who had undergone surgical treatment was higher in the younger group but there was no significant difference in the overall outcomes between the two groups.
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KEYWORD
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Cerbral Infarcion, Subtypes, Risk factor, Elderly, surgery, prognosis
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